Non-opposable triphalangeal thumb in an Italian family.
نویسندگان
چکیده
This report describes a family with bilateral non-opposable triphalangeal thumb, bringing to two the number of families with this autosomal dominant disorder.
منابع مشابه
Familial opposable triphalangeal thumbs associated with duplication of the big toes.
A rare association of triphalangeal thumbs and duplication of the big toes is described. The family pedigree confirms autosomal dominant inheritance with marked penetrance. A systematic approach to the diagnosis of this anomaly is presented. The distinction between the two types of triphalangeal thumb, true (opposable) and finger-like (non-opposable), is emphasised.
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Triphalangeal thumb is characterized by the interposition of an extra-phalanx between two normal ones. In this article the authors present the case of a 24-year-old man with bilateral triphalangeal thumb of opposable type, without any other associated anomaly or genetic syndrome. The patient had triangular delta extra-phalanxes that caused ulnar deviation of both thumbs. Surgical procedure for ...
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Triphalangeal thumb is characterized by the interposition of an extra-phalanx between two normal ones. In this article the authors present the case of a 24-year-old man with bilateral triphalangeal thumb of opposable type, without any other associated anomaly or genetic syndrome. The patient had triangular delta extra-phalanxes that caused ulnar deviation of both thumbs. Surgical procedure for ...
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Triphalangeal thumb (TPT), a rare malformation of uncertain pathogenesis, may occur as an isolated defect, in association with other malformations of the hands, or as a feature of a syndrome or sequence. Isolated TPT occurs in two functional types: opposable and non-opposable. The latter appears to be inherited as a simple autosomal dominant trait, while the former is generally sporadic. TPT is...
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Triphalangeal thumb‑polysyndactyly syndrome (TPT‑PS) is an autosomal dominant disorder with complete penetrance and a variable expression consisting of opposable triphalangeal thumbs, duplication of the distal thumb phalanx, pre‑axial polydactyly and duplication of the big toes (hallux). The causative gene of TPT‑PS has been mapped to 7q36.3. Sonic hedgehog (SHH) expressed in the zone of polari...
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ورودعنوان ژورنال:
- Journal of medical genetics
دوره 25 5 شماره
صفحات -
تاریخ انتشار 1988